CHAPS

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SKU: DG049-XX Category:
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Description

Type: Zwitterionic detergent
 
Full Name: 3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulfonate
 
Mol. Formula: C32H58N2O7S
 
Mol Weight: 614.9
 

Form: White solid

 

Purity: >99%

 
Solubility: Water soluble
 

Conductivity: <25µS in a 10% solution

 

Critical micelle concentration (CMC): 6-10mM (25°C)

 

Aggregation number: 10

 

Cloud point: >100°C

 
Average micellar weight: 6150
 

Features

  • Zwitterionic detergent
  • Non-denaturing
  • Electrically neutral

 

Applications

  • Has all the advantages of sulfobetaine containing detergents: hydrophobic, bile salt, and anionic detergents in a single molecule.
  • Better at solubilizing proteins and breaking protein-protein interactions.
  • Less protein aggregation than non-ionic detergents.
  • Capable of solubilizing opiate receptors.
  • CHAPS can be removed from protein solutions with a detergent removing gel or by dialysis.

 

 

Additional information

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