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SKU: DG049-XX Category:
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Type: Zwitterionic detergent
Full Name: 3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulfonate
Mol. Formula: C32H58N2O7S
Mol Weight: 614.9

Form: White solid


Purity: >99%

Solubility: Water soluble

Conductivity: <25µS in a 10% solution


Critical micelle concentration (CMC): 6-10mM (25°C)


Aggregation number: 10


Cloud point: >100°C

Average micellar weight: 6150


  • Zwitterionic detergent
  • Non-denaturing
  • Electrically neutral



  • Has all the advantages of sulfobetaine containing detergents: hydrophobic, bile salt, and anionic detergents in a single molecule.
  • Better at solubilizing proteins and breaking protein-protein interactions.
  • Less protein aggregation than non-ionic detergents.
  • Capable of solubilizing opiate receptors.
  • CHAPS can be removed from protein solutions with a detergent removing gel or by dialysis.



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