FCCP [Carbonyl cyanide 4-(trifluoromethoxy) phenylhydrazone]

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SKU: 786-1316-XX Category:
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Description

FCCP [Carbonyl cyanide 4-(trifluoromethoxy) phenylhydrazone] is a potent uncoupler of oxidative phosphorylation in mitochondria. It is used as a positive control for mitochondrial membrane depolarization.

FCCP disrupts the synthesis of ATP by trnasporting protons across mitochondrial inner membrane. It depolarizes the mitochondrial membrane potential.

 

Features:

  • Molecular weight:254.17
  • Cas number: 370-86-5
  • Solubility: Soluble in DMSO (100 mM). Soluble in methanol, ethanol and acetone to 20 mg/ml. Insoluble in water.
  • Molecular Formula:C10H5F3N4O
  • Stability: Stable at 4°C under desicating conditions for 1 year. Store at -20°C for long term storage. Store the dissolved FCCP in aliquotes at -20°C
  • Recomended working concentration of FCCP for cells is 20 µM. It may vary depending on cell types and should be optimized by user 

Applcation(s)

  • FCCP [Carbonyl cyanide 4-(trifluoromethoxy) phenylhydrazone] is a potent uncoupler of oxidative phosphorylation in mitochondria. It is used as a positive control for mitochondrial membrane depolarization.

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