Cephalexin is a cephalosporin antibiotic which disrupts the synthesis of the peptidoglycan layer of bacterial cell walls. Peptidoglycan synthesis is aided by transpeptidase known as pencillin-binding proteins (PBP). Cephalexin inhibits PBP3 and other penicillin-binding proteins (PBPs).
Immobilized Cephalexin is made by covalently coupling cephalexin to 6% cross linked agarose and is used for isolating cephalexin binding proteins, receptors and specific antibodies.
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Cephalexin coupled to 6% cross-linked Agarose
Coupling is covalent through linkage of amino or carboxyl group depending upon the antibiotic to the pre-activated agarose.
Available in 5 ml and 10 ml sizes
- Immobilized Cephalexin is used for purification of cephalexin binding proteins or receptors or specific antibodies.