Immobilized Papain

Web Scientific is moving...

You can now find all Web Scientific products on our parent company's site, this site will be closing on 1st of June 2021. Please place all orders via Thistle Scientific.

Click the link below to see this product on our new website.

View Product
SKU: 786-790-XX Category:
Special Requirements?


Papain is a cysteine protease enzyme (EC that has the endopeptidase activity to cleave immunoglobulin G molecules in the hinge region.  This cleavage results in the generation of three ~50kDa fragments; two Fab domains and a Fc domain.  The papain-digested antibody is unable to promote agglutination, precipitation, opsonization, and lysis. 


The Fab and Fc fragments can be further separated with either Immobilized Protein A or ion exchange chromatography. 


Immobilized Papain is a convenient reagent for producing Fab and Fc fragments as it avoids the need to remove the papain enzyme after digestion.


Click here to request bulk or custom sizes.



  • Generate Fc and Fab from IgG
  • Eliminates contamination with papain enzyme
  • Can be used in virtually all scenarios using free papain



Additional information




SKU SizeDescription Price