Urea is a strong chemical to aid in the denaturation of proteins. Denaturants, or chaotropes, disrupt water interactions resulting in the solubilization of hydrophobic proteins and peptides. The chaotropes also act on all proteins to unfold them and alter their three-dimensional structure.
- CAS Number: 57-13-6
- Molecular Weight: 60.07 g/mol
- Chemical Formula: CH4N2O
- Denaturation of proteins
- Solubilization of proteins and peptides